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Tight regulation of CDO activity may facilitate maintenance of relatively low steady-state Cys concentrations so that Cys is available for essential functions (e.g., protein, CoA, glutathione, and H 2 S synthesis) while also preventing high Cys concentrations, which could be toxic

10.1016/j.neuroscience.2009.04.042 141 ShenX.LiuX.WanS.FanX.HeH.WeiR.et al (2019)

Peripheral blood mononuclear cells, isolated from blood type-matched donors to mimic transplantation, were introduced into the tissue to measure immune responses